Studies in humans and other primates have been focused on several structures, such as the amygdala, the prefrontal cortex, the superior temporal sulcus, the anterior cingulate cortex and some .

The long muscles of head and neck are anterior to the cervical vertebrae, most of them in the sulcus.

Generally, the anterior line of the coronal sulcus was indistinct, whereas the posterior line was clear and easy to be identified.