Elevation NH3 occurs as the toxic metabolite inhibits the carbomyl phosphate synthaseI, preventing the incorporation of NH3 into the urea cycle.
增多的氨作为毒性代谢物抑制了氨甲酰磷酸合成酶，并阻止氨进入尿素循环。
2
A polyketide synthase complex composed of polyketide synthase with 15 total modules, a non-ribosomal peptide synthetase with I module, and a cytochrome P450 hydroxylase is described.