A few drugs have harmful effects when used together and should not be combined (an example is stavudine and zidovudine).
某药物一起使用时的会产生有害影响，不应组合使用(例如司他夫定和齐多夫定)。
2
Zidovudine may competitively inhibit the intracellular phosphorylation of stavudine. Therefore, use of zidovudine in combination with Stavudine is not recommended.
齐多夫定会竞争性抑制司他夫定的磷酸酰化，因此禁止与齐多夫定联合用药。
3
The stavudine was prepared from 5-methyluridine via six steps in 34% overall yield, in which the key step is the selective acylation of 5-methyluridine by propionyl chloride.