Irreversible inhibitor of Thrombin and other serine proteases. Inhibits by acylation of the active site of the enzyme. Much less toxic than PMSF and DFP.
凝血酶及其他丝氨酸蛋白酶的不可逆抑制剂,将活性位点酰基化。比PMSF和DF P毒性小得多。
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AIM to investigate the apoptotic effect of thrombin on brain microvascular endothelial cell (BMVEC) of cultured rat, and the protective effect of hirudin, an inhibitor of thrombin.