Taxadiene synthase, a diterpene cyclase, catalyzes the conversion of geranylgeranyl diphosphate (GGPP) to taxadiene, a key intermediate in Taxol biosynthesis in yew.
紫杉烯合酶是一种二萜环化酶，催化牛儿基牛儿基焦磷酸形成紫杉醇生物合成过程中的中间体紫杉烯。
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Taxadiene synthase is the first known, and the most important, enzyme involved in taxol anabolism, which catalyzes the first committed, and a slow but not rate-limiting, step of taxol biosynthesis.