Results: Protein and mRNA of VEGF were located in endothelial cells of vascular and breast cancer cells, the expression level was elevated while the clinical staging of tumor progressed.

Lung cancer staging is a validated tool that involves careful identification of the tumor, lymph node involvement, and metastatic spread.

Extent, description and staging of the tumor is based primarily on imaging as the region is inaccessible to a complete and satisfactory clinical examination.