The whole concept of estrogenreplacementtherapy was about that.
雌激素替代疗法的整个概念就是针对它的。
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Hormonal changes. Women — if you're on hormone replacementtherapy (HRT), you've probably learned firsthand that extra estrogen can cause a weight gain in fat, not muscle.
In the 1980s and 1990s, breast cancer rates steadily increased, in parallel with the rise in obesity and the use of hormone replacementtherapy, which involves estrogen.