Warfarin therapy should be discontinued when warfarin is suspected to be the cause of developing necrosis and heparin therapy may be considered for anticoagulation.
当怀疑华法林治疗引起坏死时，则须停止治疗，并且考虑使用肝素治疗。
2
If possible, estrogen therapy should be discontinued at least 4 to 6 weeks before any surgery associated with an increased risk for thromboembolism or during periods of prolonged immobilization.
如果可能，在进行可能会增加血管栓塞风险或将会长期不活动的手术之前，雌激素疗法应该停止4到6周。
3
Warfarin therapy should be discontinued when Warfarin is suspected to be the cause of developing necrosis and heparin therapy may be considered for anticoagulation.