The solubility, stability in gastrointestinal tract, membrane permeability and presystemic metabolism of drugs were the major factors on oral drug absorption.
药物的溶解性，在胃肠道中的稳定性，膜的通透性和全身代谢是影响口服药物吸收的主要因素。
2
The importance of the toxicological risk assessment is to ensure that these leachables do not adversely affect the stability or efficacy of the drug product.
毒理学风险评估的重要性是为了确保这些浸出物不会对药品的稳定性和有效性产生负面影响。
3
Because you did not adequately study the drug as part of a stability program, you were not made aware of the product separation issue until the product was already in the hands of consumers.