It has been called in question on clinical safety, even not accepted by international market, due to toxical SemenStrychni as monarch drug which often induce adverse reaction.
但因其君药马钱子毒性较大，临床常有不良反应报道，从而影响该药的临床安全使用及国际准入。
2
Objective to clarify the main component of acute toxic effect in Shufeng Huoluo pills, and the effects of other components from Shufeng Huoluo pills on acute toxic effect of SemenStrychni.
目的阐明疏风活络片急性毒性作用的主要组分，以及其他组分对马钱子急性毒性的影响。
3
ResultsAcute toxic manifestations of Shufeng Huoluo pills were twitch, entasia, which resemble acute toxic symptoms of SemenStrychni.