Results: The new gene encoding the antigen epitope of SARS-CoV Sprotein was designed and synthesized successfully, and it was highly expressed in E coli.
Of three forms of S recombinant proteins, only S or S1 protein induced neutralizing antibody responses, antibody titer was increased by Sprotein immunization.
其中,仅S和S1蛋白重组质粒能够诱导中和抗体的产生,以S蛋白的效价为高。
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The difference of sprotein will not only cause the change of the host but will also lead to the cold, peritonitis, gastroenteritis and many diseases of the host.