SH-SY5Y cells are an adrenergic clone of the human neuroblastoma cell line SK-N-SH and a very useful model for the study of neuronal cell terminaldifferentiation.
BMP may induce mesenchymal cells to differentiate into chondrocytes, promote the synthesis of extracellular matrix and inhibit the terminaldifferentiation of chondrocytes.
BMP分子可以诱导间充质细胞分化为软骨细胞,促进合成细胞外基质,抑制软骨细胞的终末分化。
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Objective To investigate the roles of mouse erythroid differentiation and denucleation factor (MEDDF), newly cloned in our laboratory, in erythroid terminaldifferentiation.