It recognized even androgen-independentcancer cells, present when prostate cancer is incurable, the study by researchers at the University of Pennsylvania showed.
宾夕凡尼亚州大学的研究者说,即便是在目前来说不可治愈的非雄激素依赖性前列腺癌中也是有效的。
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AIM: To study the role of androgen receptor (AR) in hormone-dependent and hormone-independentprostatecancer cell proliferation by knocking down AR expression with adenovirus-delivered siRNA.
The mutation of androgen receptor gene, abnormal phosphorylation and abnormal regulation of co-activators contribute to the formation of androgen-independentprostatecancer.