We must plough on somehow in spited all the difficulties.
不管怎样我们都应不顾困难，坚持下去。
2
The couple rubbed along together for years in spited of occasional disagreements.
多年来，尽管这对夫妇偶尔有些不和，他们还过得去。
3
Many hospitals still isolate new-born babies from their mothers, in spited of modern medical opinion that this practice is harmful to both mother and child.