This model has considered many sorts of medium, the simulation of excavation process and construction sequence, and the semi - infinite plane of surface factor as well.

To compute the mean of many time shift values by shifting time window can help to eliminate the interference of random and other noises with surface factor, thus lineup statics may be obtained.

Erbitux, for example, binds to a cell-surface protein called epidermal growth-factor receptor (EGFR).