The kinetochores are the macromolecular structure that is associated with the centromeres of chromosomes and serves as the site of spindlemicrotubule attachment during mitosis.
着丝点是一个大分子物质，位于染色体的着丝粒上，在有丝分裂期间，是纺锤体微管附着的位置。
2
Microtubule dynamic instability allows probing for microtubule anchor sites, and can be coupled to spindle positioning force generation.
微管的动态不稳定性允许探测微管锚网站，并可以结合主轴定位部分的构成。
3
Taxol can inhibit mitosis of the microtubule network renewable, prevent mitotic spindle lead to the formation of chromosome break, inhibit the replication of tumor cells.