The synthesis of Cilastatinsodium started from ethyl acetoacetate and 1-bromo-5-chloropentane, through 3 steps to produce ethyl 7-chloro-2-oxoheptanoate;
ABSTRACT: OBJECTIVE: to analyze and compare the cost-effectiveness of domestic and imported imipenem and cilastatinsodium for severe lower respiratory tract infection.
摘要：目的：分析国产与进口亚胺培南西司他丁钠治疗重症下呼吸道感染的成本-效果，并进行比较。
3
RESULTS: Infections in the patients given imipenem cilastatinsodium were rapidly controlled and the effects of which were definite.