Biaryl substituted pyrazole compounds are sodiumchannelblockers useful for the treatment of pain and other conditions.
联芳基取代吡唑化合物为钠通道阻滞剂，用于治疗疼痛和其它病症。
2
Biaryl substituted pyridine, pyrimidine and pyrazine compounds are sodiumchannelblockers useful for the treatment of pain.
联芳基取代的吡啶、嘧啶和吡嗪化合物为用于治疗疼痛的钠通道阻滞剂。
3
Here we show that charged sodium-channelblockers can be targeted into nociceptors by the application of TRPV1 agonists to produce a pain-specific local anaesthesia.