A thinly scattered permanent population and development of leisure activities, particularly skiing, have resulted in significant long-term changes to the local ecosystems.
稀稀落落的常住人口和休闲活动（尤其是滑雪）的发展，导致当地生态系统发生了重大的长期变化。
2
He said if it continues, there is the potential for a significant long-term impact on U.S.-Russia relations.
他说，如果俄罗斯继续这样作，这有可能对美国和俄罗斯的关系产生长期的重要影响。
3
The updated view may add to fears that long-term unemployment is a significant threat.