OBJECTIVE To prepare thymopentin microspheres and investigate the drug release in vitro.
目的制备胸腺五肽微球并对其体外释放进行考察。
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Methods Using HPLC method, we investigated the influence of different temperature, sonification time and pH value on thymopentin.
方法采用高效液相色谱法(HPL C),研究胸腺五肽在不同温度、超声时间及p H值条件下的稳定性。
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The results show that the major component of the crude peptide is the target peptide thymopentin and the main by-products are derived from incomplete deprotection of the desired peptide.