Vittorio Missoni and his wife were among six people on board the flight from the archipelago of Los Roques towards Caracas' Maiquetia airport.
BBC: Missoni boss missing as Venezuela plane disappears
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"There's a new generation of entrepreneurs who are becoming more tech-savvy and not betting on careers where they stay in the same company forever, " says Roques.
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Los Roques, an archipelago made up of dozens of islands some 95 miles (150km) off Venezuela's coast, is one of the area's most popular holiday destinations.
BBC: Missoni boss missing as Venezuela plane disappears