One of the telltale signs of this disease is the deposit of beta-amyloid plaques in the brain.
这种疾病的众多隐秘信号之一是在脑中的B -淀粉样蛋白斑块中的沉积。
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When stained with Congo red and observed under polarized light, the amyloid has a characteristic "apple green" birefringence as seen here in a deposit around an artery in the heart.
Usually amyloid fibrils form and deposit in the vicinity of the target cells and accumulate on the cell membrane, triggering a cascade of cellular events which lead to apoptosis.