When not blocked by peptide 15-1, hyaluronan fragments bind to skin cell receptors and set off a signaling cascade that increases inflammation at the site of the injury.
当没有被肽15-1阻隔,透明质酸碎片附着在受体的表皮细胞并且在受伤部位产生显著的层叠而加速发炎。
2
These alterations defined a core set of 12 cellular signaling pathways and processes that were each genetically altered in 67% to 100% of the tumors.
这些改变被定义为一组12个核心的细胞信号通路和过程,每个通路在肿瘤有67%到100%的改变。
3
We set up in collaboration with him and this allowed us to show that Notch signaling was in fact highly enriched in stem cells, and was rapidly shut off as stem cells differentiated.