Objective: To design the formulation of selfemulsifying drug delivery system for silymarin and evaluate its dissolution.
目的:设计水飞蓟素自乳化系统处方并评价其溶出度。
2
Result: The silymarin selfemulsifying drug delivery system was composed of Tween 85, olive oil and glycerin but not including silymarin.
结果:水飞蓟素自乳化系统除主药外,主要由吐温85、橄榄油、甘油组成。
3
The characters, mechanism and formulation design of selfemulsifying drug delivery system were reviewed. Its quality and affecting factors, and pharmaceutical applications were discussed.