While a professor at Georgetown University, he studied the antihistamine Seldane, which had been found to cause health problems.
FORBES: Pharmaceuticals
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But Aventis researchers tweaked Seldane to get rid of its big liability it caused irregular heart beats and Allegra was born.
FORBES: Great News For Hayfever Sufferers
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As precedent he cites the example of Seldane, an antihistamine developed by Hoechst Marion Roussel (now Aventis (nyse: AVE - news - people )) to treat hay fever.