The molecular mechanism and physiological function of recoding by A-to-I RNAediting is well known, but its evolutionary significance remains a mystery.
RNA编辑的分子机制和生理功能的研究已经非常广泛，但其在生物进化过程中的意义仍然是一个谜团。
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Then along came RNAediting, in which guide RNAs or enzyme action modify some messenger RNAs such that the final protein sequence cannot be deduced from the gene sequence alone.
Such small antisense RNAs may later have gained a role in RNAediting, possibly under selective pressure to repair a region or restore a reading frame after loss or erosion of a module.