Cefixime open sidechain acid was prepared by oximation, etherification, chlorination, ester decomposition using t-butyl acetoacetate as starting material.
以乙酰乙酸叔丁酯为原料,经过肟化、醚化、氯代酯解反应合成了头孢克肟开环侧链酸。
2
The technology and equipment for the process of side-chainchlorination, oxidation, diazotization and coupling are introduced.