A series of esters of tertiary alcohols have been effectively synthesized byacylation and the DCC methods.
本文采用酰化法和DCC法合成了一系列叔醇酯。
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Irreversible inhibitor of Thrombin and other serine proteases. Inhibits byacylation of the active site of the enzyme. Much less toxic than PMSF and DFP.
凝血酶及其他丝氨酸蛋白酶的不可逆抑制剂,将活性位点酰基化。比PMSF和DF P毒性小得多。
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METHODS: The title compounds were synthesized byacylation of twelve acyl chlorides and two intermediates prepared by Friedel Crafts reaction, lengthening of carbon chain, hydrolysis and cyclization;