AIM: To introduce and evaluate a canine model of secondary hypersplenism induced by splenic vein ligation.
目的：介绍并评价脾静脉结扎诱导的继发性脾功能亢进犬动物模型。
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Conclusion The method of splenic vein ligation to induce experimental secondary hypersplenism is a simple, effective and relatively ideal model for surgical or interventional therapy in hypersplenism.
结论脾静脉结扎建立继发性功能亢进方法简单、确切，可以作为脾功能亢进外科或介入治疗的较理想模型。
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A canine model of secondary hypersplenism was established by ordinal ligation of gastrosplenic vein trunk, splenic vein and its collateral branches.