Wire fixation brought about secondary bone healing (traditional bone healing). The study suggests that the quality of bone healing by compression fixation is superior to wire fixation.

X-rays and other forms of radiation were known to kill cells and these were aimed at lymph glands near and distant, on sites of secondary cancer spread in bone and lung and brain.

Secondary conditions include chronic inflammatory diseases, immobilization for long periods, endocrine or hematologic diseases, and cancer and associated treatments that adversely affect bone.