Methods. Mechanics were measured after sham phosphate buffered saline injection with a 27 G or 33 G needle in the rat and with a 27 G needle in the sheep.

Objective to assess the safety and tolerance of single-dose and continuous intravenous drip of Xuesaitong saline injection in Chinese volunteers, thus to establish the effective clinical dosage.

In both groups, patients received an injection of saline into the catheter.