Karsenty's team further found that the boneresorption process creates an acidic environment that converts osteocalcin into an "active" form, which can escape bone and enter circulation.
Drugs that inhibit boneresorption [which are commonly used to treat osteoporosis] may, in certain patients, favor glucose intolerance, "Karsenty says."
而用于抑制骨吸收的各种药物(这些药物通常被用于治疗骨质疏松)有可能在一些特定的病人身上提升糖耐量。
3
Therefore, insulin's effects on the bones favors boneresorption.