Whole glucan particles enhance the tumoricidal activity of the innate immune system by binding to the C3 complement protein receptor CR3.

Objectives to develop a highly sensitive and reproductive test for the number of complement receptor 1 on erythrocytes (ECR1), and to investigate the significance of ECR1 in immune relative diseases.

This review focuses on the role of two major components of innate immunity in the context of ischemia-reperfusion injury: the Toll-like receptor and the complement system.