The new GH isoform differed from classical growth hormone which had 2 GH receptorbinding sites, and there was only one GH receptorbindingsite in the new GH isoform molecule.
Virus from one of the patients shows mutations at the receptor-bindingsite.
来自患者之一的病毒显示在受体结合部位突变。
3
However, binding efficiency varies between flu strains, and that variation is partly determined by the receptor-bindingsite (RBS) within the hemagglutinin protein.