Conclusion: the pulsatilerelease of aspirin can be controlled by selection of disintegrants of the core and changing composition and thickness of the coating film.
CONCLUSION:The pulsatilerelease of ditiazem hydrochloride could be controlled by adjusting the composition of the outer shell materials and the manipulation condition.
结论：通过调整处方和工艺，可以得到体外不同时间脉冲释药的盐酸地尔硫上（艹）下（卓）片剂。
3
Objective: to investigate the factors involved in the release in vitro degree of terbutaline sulphate pulsatile controlled release pellets.