The researchers built on fundamental discoveries on the structure and replicationofDNA made by Nobel laureates James Watson, Francis Crick and Arthur Kornberg.
Antisense RNA exists in all kinds of living beings wildly. It ACTS on the course of the replicationofDNA, transcription and translation, which realize the regulation and control of gene expression.
反义rna广泛存在于各类生物中,它作用于DNA的复制、转录、转译的过程,实现对基因表达的调控。
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Szostak said: "When we started the work, we were really just interested in the very basic question about DNAreplication, how the ends of chromosomes are maintained."