Acute ischemic cerebrovascular disease is one of the three principal diseases causing people to death in which seconded only to heart disease and cancer, but it is the main reason of disabled people.
急性缺血性脑血管病是导致人类死亡的三大主要疾病之一，仅次于心脏病及癌症，但却是病残的主要原因。
2
Such risk factors and behaviours can lead to some of the principal causes of death, disease and disability.
这类危险因素和行为有可能成为导致某些死亡、疾病和残疾的主要原因。
3
Apart from relapse of a person's disease, GVHD is the principal cause of death in patients who have received donated bone marrow.