The major inclusion criterion was admission to an acute carefacility with a principal diagnosis of ischemic stroke.

Instead, they have adopted a "dimensional" approach, in which patients are assessed for symptoms besides those that match their principal diagnosis, as well as for the severity of their symptoms.

For the sake of better carrying on fault detection and diagnosis, introduced the theory of principal component analysis (PCA) and the mechanism and strategy based on PCA for the fault of process.