Asialoglycoproteinreceptor (ASGPR) is a specific receptor of mammalian hepatocytes. Reduction in ASGPR concentration has been proven to appear in liver cirrhosis and liver cancer.
Asialoglycoproteinreceptor, transferrin receptor and receptors for lactoferrin, insulin, epidermal growth factor, folic acid and mannose have been used in receptor-mediated gene delivery.