However, the current Nature Genetics report associates SLE with a polymorphism at gene TNFSF4.

For example, transfer of virulence gene and transmission of drug-resistant gene mediated by a phage results in gene polymorphism of bacteria, which is an important problem in medicine and genetics.

The individual variation may be caused by many factors, such as genetics, environment, disease stage and diet, etc, among which genetic polymorphism is a common and uncontrollable factor.