For example, RNApolymeraseII is found concentrated at the promoters of thousands of genes, causing much interest in the field to shift focus to the role of elongation in regulating gene expression.
P-TEFb is a general transcription factor that regulates transcription elongation through phosphorylation of the C-terminal tail domain (CTD) of RNApolymeraseII (RNAP II).
P - TEFb是一个普通的转录因子,它通过磷酸化rna聚合酶ii (RNAP II) C -末端尾巴结构域(CTD)来调节转录延伸。
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Actin was also reported to co-purify with RNApolymeraseII and to be required for efficient in vitro transcription by RNApolymeraseII.