Many suffered from a definable alcohol, drug, or mental disorder.
许多人因可识别的酒，药品或精神障碍而遭受痛苦。
《柯林斯英汉双解大词典》
2
Bipolar disorder may appear to be a problem other than mental illness-for instance, alcohol or drug abuse, poor school or work performance, or strained interpersonal relationships.
People with borderline personality disorder, who struggle to control their impulses and anger, often resort to drugs and alcohol to soften their intolerable moods.