Coffee also stimulates the release of cholecystokinin, a hormone which inhibits cholesterol build-up in the gallbladder.

Moreover osteocalcin also sends signals to fat cells directly, causing them to release another hormone called adiponectin that makes the body more sensitive to the effects of insulin.

Activation of the vagus nerve is also linked to the release of a hormone called oxytocin, which generates warm, calm feelings - just the sort associated with elevation.