AIM: To study the effect of phenylmethylsulfonyl fluoride (PMSF), a phospholipase C inhibitor, on ischemic injury to brain mitochondria in rats.
目的:研究磷脂酶C抑制剂PMSF在缺血性脑线粒体损伤中的作用。
2
Irreversible inhibitor of Thrombin and other serine proteases. Inhibits by acylation of the active site of the enzyme. Much less toxic than PMSF and DFP.
凝血酶及其他丝氨酸蛋白酶的不可逆抑制剂,将活性位点酰基化。比PMSF和DF P毒性小得多。
3
PMSF completely inhibited the fibrinolytic activity, but EDTA and EGTA exerted little effect on it. These results demonstrate that DFE is a serine protease.