Methods Specimens were obtained from 30 patients with rectumadenocarcinoma, and examined for the expression of VEGF-C and VEGFR-3 in carcinoma region and normal region.
Conclusion the overexpression of VEGF-C and VEGFR-3 in rectumadenocarcinoma may promote the hyperplasia and dilation of lymphatics, and the lymphatic metastasis of the cancer cells.