The tumor cells produce a whole range of proteases that degrade the proteins of the extracellularmatrix that hems them in, part of which is the basement membrane.
这些肿瘤细胞产生了一整系列的蛋白酶,能降解包围它们的细胞外基质蛋白,这也是部分的基底膜。
2
However, proteins outside cells form the extracellularmatrix (ECM), which is essential for cell functions.
然而,细胞外的蛋白质形成了细胞外基质,它们是细胞功能所必需的。
3
Conclusion: in vitro high glucose solution increased mesangial cell synthesis of extracellularmatrixproteins.