At previtellogenic stage (that is, at pupal stage), large amounts of protein granules and mitochondria were present in fat body cells, but no rough endoplasmic reticulum (RER) could be observed.

Those with brown granules in the nucleus of vascular endothelial cells were PCNA protein positive.

There are more protein bands in SDS-PAGE than in PAGE, so secretion-excretions and subcellular secretion granules contain the multimeric proteins.