Pfam is a large collection of multiple sequence alignments and hidden Markov models covering many common proteinfamilies.
为一包含了许多多重序列校准,以及“隐藏式马尔科夫模型”的巨大集合,里面涵盖了许多常见的蛋白质家族。
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One encouraging finding: most of the genetic defects identified in the Middle Eastern families were not in the business part of the gene -the part that codes for a critical brain protein.