Acyl-CoA: cholesterolacyltransferase(ACAT) is an intracellular enzyme that catalyzes the formation of cholesterol esters from long-chain fatty acylcoenzymeA and cholesterol.
Objective: To investigate the role of taurine in acyl-coenzymea: cholesterolacyltransferase-1 (ACAT-1) expression and activity in THP-1 and THP-1-derived macrophages.