Pharmacodynamic assay has shown that inhibition of proteasome is dose dependent and reversible.
药效学分析表明蛋白酶体抑制药的抑制作用有剂量依赖性和可逆性。
2
P42 is one subunit of 19s regulatory complex of 26s proteasome in ubiquitin-proteasome pathway, and it is also one subunit of modulator, which is 19s regulatory complex dependent.
p 42是泛素蛋白水解酶通路中26s蛋白水解酶复合体19s帽状调节复合物的一个亚基,也是组成19s调节复合物依赖的蛋白水解酶调节子的一个组成成分。